• Establishment of killer whale (Orcinus orca) primary fibroblast cell cultures and their transcriptomic responses to pollutant exposure 

      Bjørneset, Juni; Blévin, Pierre; Bjørnstad, Pål Marius; Dalmo, Roy Ambli; Goksøyr, Anders; Harju, Mikael; Yadetie, Fekadu; Routti, Heli Anna Irmeli; Limonta, G.; Panti, C.; Sundaram, A.Y.M.; Rikardsen, Audun H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-02)
      Populations of killer whale (Orcinus orca) contain some of the most polluted animals on Earth. Yet, the knowledge on effects of chemical pollutants is limited in this species. Cell cultures and in vitro exposure experiments are pertinent tools to study effects of pollutants in free-ranging marine mammals. To investigate transcriptional responses to pollutants in killer whale cells, we collected skin ...
    • Establishment of killer whale cell cultures and their responses to pollutant exposure 

      Bjørneset, Juni (Master thesis; Mastergradsoppgave, 2022-03-15)
      The cosmopolitan apex predator killer whale (Orcinus orca) is one of the species worldwide with the highest levels of persistent organic pollutants (POPs) in their tissues. The knowledge of how POPs may affect the species is limited, likely due to the ethical, legal, and practical challenges of researching toxicology on free-ranging marine mammals. The use of in vitro models has proved to be a ...